siRNA Targeting Beta Secretase (BACE)
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United States of America Patent
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Issued Date -
Jan 24, 2013
app pub date -
Sep 13, 2012
filing date -
Nov 14, 2002
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Abstract
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for BACE.
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