Methods and Systems for Measurement of Tear Glucose Levels

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United States of America Patent

APP PUB NO 20130008803A1
SERIAL NO

13342634

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Abstract

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A sensor system for determining glucose concentration in a tear fluid sample includes a working electrode including an immobilized glucose oxidase enzyme portion for reacting with glucose in the tear fluid sample, and a selectivity portion for enhancing the selectivity for glucose over electroactive interferent species in the tear fluid sample. Alternatively, a vessel for receiving the tear fluid sample may include the enzyme portion on an inner wall thereof. A reference electrode is disposed adjacent the working electrode, wherein the electrochemical reaction of the enzyme portion with glucose in the tear fluid sample generates a current related to the glucose concentration in the tear fluid sample.

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Patent Owner(s)

Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY OF MICHIGANC/O INNOVATION PARTNERSHIP 1600 HURON PARKWAY 2ND FLOOR ANN ARBOR MI 48109

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cohan, Bruce E Ann Arbor, US 9 527
Flanders, Zvi Ann Arbor, US 7 372
Meyerhoff, Mark E Ann Arbor, US 53 1054
Peng, Bo Ann Arbor, US 164 759
Yan, Qinyi Davie, US 8 20

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