METHOD AND DEVICE FOR DETERMINING A RISK OF GRAFT REJECTION

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United States of America Patent

SERIAL NO

13516707

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Abstract

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The invention relates to a method for determining a risk of permanent rejection of a graft after being transplanted to a recipient, said method being characterized in that it includes the following steps: (a) entering physiological/clinical characteristics of the recipient and the donor into a computation unit by means of an input interface, said characteristics including the gender of the recipient, the creatinine level of the graft donor when sampled, the age of the recipient at the time of the transplant,—the number of renal transplants previously received by the recipient,—a creatinine level of the recipient measured twice at at least one predetermined point in time after the transplant, a proteinuria level of the recipient measured at a predetermined point in time after the transplant, and the existence of an episode of permanent rejection of the transplant during the first year of the transplant; (b) determining the parameters on the basis of said characteristics; (c) combining said parameters so as to obtain a risk score of permanent rejection of the gait; and (d) analyzing said risk score so as to determine a risk of permanent rejection of a graft.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)101 RUE DE TOLBIAC PARIS 75013
UNIVERSITE DE NANTESNANTES FRANCE NANTES LOIRE-ATLANTIQUE
CHU NANTES44000 NANTES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Daguin, Pascal Nantes, FR 1 5
Foucher, Yohann Nantes, FR 2 7
Giral, Magali Carquefou, FR 8 9
Soulillou, Jean-Paul Nantes, FR 15 97

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