BUFADIENOLIDE DERIVATIVES, PREPARING PROCESS THEREOF, COMPOSITION COMPRISING THE SAME AND THE USE THEREOF

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United States of America Patent

APP PUB NO 20130005696A1
SERIAL NO

13508827

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Abstract

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The present invention provides a class of bufadienolide derivatives representing by the following formula I or pharmaceutically acceptable salts thereof, the preparing process thereof, pharmaceutical composition comprising the same and the use thereof. The bufadienolide derivatives have inhibitory activities against human-derived tumor cell lines, and thus can be used as a drug for treating malignancies.

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Patent Owner(s)

Patent OwnerAddress
SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES201203 555 ZHANGJIANG ROAD ZHANGJIANG PUDONG NEW AREA SHANGHAI SHANGHAI CITY SHANGHAI CITY 201203

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guo, Dean Shanghai, CN 5 32
Hu, Lihong Shanghai, CN 71 133
Lei, Min Shanghai, CN 25 81
Liu, Xuan Shanghai, CN 214 1967
Ma, Biao Shanghai, CN 52 180
Xiao, Zhiyong Shanghai, CN 9 31

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