ARTIFICIAL PEPTIDE AND USE THEREOF
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United States of America Patent
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app pub date -
Sep 12, 2012
filing date -
Jan 25, 2008
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Abstract
Disclosed is a method for transforming human or non-human mammalian stem cells by introducing a desired peptide motif into the stem cells. The stem cell transformation method disclosed herein uses a synthesized peptide having an amino acid sequence which constitutes the desired peptide motif on the N-terminal end or C-terminal end of a cell membrane-permeable nucleolar localization signal sequence defined by the amino acid sequence KKRTLRKNDRKKR (SEQ ID NO:1).
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