ANTIBODY AGAINST SEROTYPE E LIPOPOLYSACCHARIDE OF PSEUDOMONAS AERUGINOSA

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United States of America Patent

APP PUB NO 20130004499A1
SERIAL NO

13579757

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Abstract

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Provided is a novel antibody having an excellent antibacterial activity against P. aeruginosa. By using plasmablasts obtained from cystic fibrosis patients with chronic P. aeruginosa pulmonary infection as starting materials, antibodies which bind to LPS of a P. aeruginosa strain of serotype E and which have excellent antibacterial activities in vitro and in vivo were successfully obtained.

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Patent Owner(s)

Patent OwnerAddress
SYMPHOGEN A/S2750 BALLERUP
MEIJI SEIKA PHARMA CO LTDCHUO-KU TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akabane, Hirotomo Yokohama-shi, JP 8 5
Andersen, Peter Sejer Vanlose, DK 13 63
Hagiwara, Yasuyo Yokohama-shi, JP 1 1
Hoshina, Yukari Yokohama-shi, JP 7 5
Inaba, Tsuneyoshi Yokohama-shi, JP 6 5
Kumagai, Masashi Yokohama-shi, JP 39 208
Nagaso, Hiroshi Yokohama-shi, JP 10 12
Okutomi, Takafumi Yokohama-shi, JP 7 7
Otsuka, Keiko Yokohama-shi, JP 10 22
Saito, Jun Yokohama-shi, JP 224 1968
Tanaka, Jiro Yokohama-shi, JP 50 403

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