DEVICES AND METHODS FOR REDUCING RADIOLYSIS OF RADIOISOTOPES

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United States of America Patent

APP PUB NO 20130004414A1
SERIAL NO

13173978

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Abstract

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Disclosed are microfluidic devices and kits for containing radioisotopes. The devices and kits comprises at least one confining geometry having a cross-section dimension below the beta(+) or beta(−) range of a radioisotope, when containing the radioisotope configured in such a way that that neighboring segments of the confining geometries are isolated from its nearest neighbor such that no measurable kinetic positron energy transfer occurs between the segments when containing the radioisotope. Methods of storage and synthesis of radiopharmaceuticals are also disclosed. In another aspect, the present invention relates to methods of storing radiotracers and synthesizing radiopharmaceuticals, using the aforementioned device. The radiotracers and radiopharmaceuticals comprises 18F, 11C, 14C, 99mTc, 123I, 125I, 131I, 68Ga, 67Ga, 15O, 13N, 82Rb, 62Cu, 32P, 89Sr, 153Sm, 186Re, 201Tl, 111In, or combinations thereof.

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Patent Owner(s)

Patent OwnerAddress
GENERAL ELECTRIC COMPANY1 NEUMANN WAY EVENDALE OH 45215

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baller, Marko Klaus Saarbruecken, DE 16 153
Boeld, Christoph Munich, DE 24 91
Rensch, Christian Friedrich Peter Munich, DE 11 46
Samper, Victor Donald Kirchseeon, DE 21 129
Ulin, Johan Urban Ingemar Uppsala, SE 3 12

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