Methods and Compounds for the Diagnosis and Treatment for Cancer

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United States of America Patent

APP PUB NO 20120329854A1
SERIAL NO

13388940

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides in vitro methods for detecting, grading or prognosticating cancer, in particular prostate cancer. The invention further provides isolated polynucleotides suitable for reducing or inhibiting the expression of protein kinase C beta I and/or II and/or alpha (and consequently the levels of histone H3 phosphorylated at threonine 6, histone H3 monomethylated at lysine 4, histone H3 dimethylated at lysine 4, histone H3 trimethylated at lysine 4) and further relates to pharmaceutical compositions comprising said polynucleotides for the treatment or prevention of cancer, in particular prostate cancer.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITATSKLINIKUM FREIBURG79106 FREIBURG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Metzger, Eric Neu-Brisach, FR 22 198
Schüle, Roland Weisweil, DE 8 10

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