Enrichment of nucleic acid targets

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United States of America Patent

PATENT NO 8529744
APP PUB NO 20120329064A1
SERIAL NO

13593143

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Abstract

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Methods and apparatus providing improved fidelity and specificity when separating nucleic acids from a sample, but without need for amplification. In particular, using the disclosed methods, it is possible to isolate a variant nucleic acid (i.e., a mutation) from a non-target nucleic acid (i.e., a wild-type) when the variant is present in the original sample at a much lower concentration than the non-target, e.g., 1:10,000, without substantial loss of the variant.

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Patent Owner(s)

Patent OwnerAddress
QUANTUM-SI INCORPORATED530 OLD WHITFIELD STREET GUILFORD MA 06437

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Marziali, Andrea North Vancouver, CA 62 582
Sood, Nitin Los Altos, US 11 128

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