BMP-2 Upregulating Compounds For Healing Bone Tissue And Screening Methods For Selecting Such Compounds
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Dec 13, 2012
app pub date -
Jun 8, 2011
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Jun 8, 2011
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Abstract
The present disclosure relates to a method to stimulate endogenous BMP-2 up-regulation in a subject which method comprises administering to a subject an effective amount of one or more of the following compounds prazosin, quinacrine, emetine, apomorphine, and debrisoquine, whereby endogenous BMP-2 up-regulation is stimulated in said subject. The endogenous BMP-2 up-regulation may enhance bone formation and/or cartilage formation.
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