METHODS FOR TREATING DISEASES
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United States of America Patent
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Issued Date -
Dec 6, 2012
app pub date -
May 6, 2010
filing date -
May 8, 2009
priority date (Note) -
Abandoned
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Abstract
The present invention relates to methods of modulating the level of inducible nitric oxide synthase (iNOS) in a cell which comprises administering to the cell a compound which modulates binding of SPRY domain-containing SOCS box protein (SSB) to iNOS, and/or a compound which modulates SSB activity in the cell. Further provided are methods of treating or preventing disease in a subject by modulating the level of iNOS in a cell, as well as compounds which modulate binding of SSB to iNOS and compounds which modulate SSB activity.
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