SYSTEM AND METHOD FOR SPECIFICITY-BASED MULTIMODALITY THREE- DIMENSIONAL OPTICAL TOMOGRAPHY IMAGING

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United States of America Patent

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13535774

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A system and method for specificity-based multimodality three-dimensional optical tomography imaging comprises steps of: optical imaging to obtain a light intensity of body surface optical signal of an imaging target; CT imaging to obtain structure volume data; establishing an equation representing a linear relationship between the distribution of the obtained light intensity of body surface optical signal of the imaging target, the obtained CT discrete mesh data and the distribution of unknown internal self-luminescence light sources; establishing a dynamic sparse regularization target function in every iteration for the equation; and reconstructing a tomography image. The present invention well considers the optical specificity of tissue, in which there is a non-uniform optical characteristic parameter distribution within the same tissue when finite element modeling is used, which is closer to the real situation, so that an accurate imaging effect is achieved.

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INSTITUTE OF AUTOMATION CHINESE ACADEMY OF SCIENCES100190 NO 95 EAST ZHONGGUANCUN ROAD BEIJING HAIDIAN DISTRICT BEIJING CITY BEIJING CITY 100190

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Inventor Name Address # of filed Patents Total Citations
HAN, Dong Beijing, CN 97 462
LIU, Kai Beijing, CN 775 7219
QIN, Chenghu Beijing, CN 3 28
TIAN, Jie Beijing, CN 85 177
YANG, Xin Beijing, CN 364 1412

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