PHARMACEUTICAL FORMULATIONS OF LORATADINE FOR ENCAPSULATION AND COMBINATIONS THEREOF
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United States of America Patent
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Nov 29, 2012
app pub date -
Jan 18, 2011
filing date -
Jan 19, 2010
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This invention relates to a loratadine formulation suitable for encapsulation into a soft gel capsule or suitable dosage unit improved functionality providing enhanced in vitro dissolution and bioavailability of loratadine. The invention also provides a formulation with improved functionality as a highly concentrated solution within a given fill volume in order to manufacture as small a capsule as possible to facilitate consumer acceptance and acceptable manufacturing costs. The invention also relates to a formulation of optimal stability for supporting fill composition compatible with the soft gel capsule dosage unit.
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