KITS FOR QUANTITATIVE DETECTION OF K-RAS MUTATIONS

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United States of America Patent

APP PUB NO 20120288862A1
SERIAL NO

13520176

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Abstract

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The present invention relates to an assay kit for quantitatively detecting k-ras gene mutations. Particularly, the present invention relates to detection method and a detection kit for K-ras gene mutations, which relates to the therapeutic efficacy of targeted molecular anti-cancer drugs. More particularly, the present invention relates to a fluorescent quantitative PCR method and kit for detecting mutations at hotspots of K-ras gene, together with the use thereof. The present invention detects the mutations at specific sites of K-ras gene, and can predict the therapeutic efficacy of anti-EGFR tyrosine kinase inhibitors. Therefore, it can provide a guidance to individualized treatments for cancer patients.

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Patent Owner(s)

Patent OwnerAddress
BEIJING ACCB BIOTECH LTDBEIJING 100094

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Zhao Beijing, CN 64 206
Xu, Junpu Beijing, CN 6 7

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