PROCESSES AND COMPOSITIONS FOR METHYLATION-BASED ENRICHMENT OF FETAL NUCLEIC ACID FROM A MATERNAL SAMPLE USEFUL FOR NON-INVASIVE PRENATAL DIAGNOSES

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United States of America Patent

APP PUB NO 20120277119A1
SERIAL NO

13495975

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided are compositions and processes that utilize genomic regions differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuplodies.

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Patent Owner(s)

Patent OwnerAddress
SEQUENOM INC3595 JOHN HOPKINS COURT SAN DIEGO CA 92121

International Classification(s)

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  • 2012 Application Filing Year
  • C12Q Class
  • 2418 Applications Filed
  • 1732 Patents Issued To-Date
  • 71.63 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
EHRICH, Mathias San Diego, US 69 1793
Nygren, Anders Olof Herman San Diego, US 17 347

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Patent Citation Ranking

  • 16 Citation Count
  • C12Q Class
  • 67.32 % this patent is cited more than
  • 13 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1957962239351241714191072301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050100150200250300350400450500550600650700750800850

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