PRODUCTION OF RECOMBINANT FACTOR IX IN A HUMAN HEPATOCYTE CELL LINE
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United States of America Patent
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Issued Date -
Oct 25, 2012
app pub date -
Nov 4, 2010
filing date -
Nov 6, 2009
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Abandoned
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Abstract
The invention relates to a recombinant human factor IX (FIX) characterized in that said factor is obtained by a preparation method comprising, or even consisting of, the steps which consist in causing the genetic material encoding the FIX to be expressed in vitro in a human hepatocyte cell line Huh7, recovering the cellular supernatant in which the FIX was secreted and, optionally, purifying the synthesized FIX.
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