Predictive Value of IL28B Gene Polymorphism Combined with Pretreatment Serum IP-10 Quantification for Response to Peginterferon and Ribavirin Is Enhanced in Comparison with any of these Biomarkers alone

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United States of America Patent

APP PUB NO 20120252695A1
SERIAL NO

13514193

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Abstract

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The current invention relates to a method of combining IL28B genotype determination with pre-treatment serum level measurement of IP-10 to predict the outcome of a sustained virological response (SVR) or non-response to peginterferon and ribavirin for individual patients infected with HCV.

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JANSSEN SCIENCES IRELAND UCCO CORK

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aerssens, Jeroen Nieuwrode (Holsbeek), BE 16 40
Fanning, Gregory Charles Woluwe St Pierre (Brussels), BE 2 4
Fried, Michael W Chapel Hill, US 1 2

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