METHODS AND MEANS TO ALTER LIPID BIOSYNTHESIS BY TARGETING MULTIPLE ENZYMES TO SUBORGANELLE DOMAINS
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United States of America Patent
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Issued Date -
Sep 20, 2012
app pub date -
Oct 19, 2010
filing date -
Oct 20, 2009
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Abandoned
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Abstract
Methods and means are provided to alter lipid biosynthesis in eukaryotic organisms by targeting at least two different polypeptides involved in fatty acid or lipid metabolism towards a similar or the same subdomain of an organelle, such as the endoplasmatic reticulum (ER), through fusion of the polypeptides with a similar or the same heterologous polypeptide targeting the chimeric fusion polypeptide to the mentioned subdomain.
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