Highly Pure Plasmid DNA Preparations
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United States of America Patent
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Issued Date -
Sep 13, 2012
app pub date -
Mar 27, 2012
filing date -
Apr 30, 2008
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Abandoned
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Abstract
The present disclosure generally relates to highly pure plasmid compositions having low, or undetectable, levels of colanic acid and other contaminants made by a process that comprises purifying plasmid DNA by chromatography, treating the purified plasmid DNA with a polypeptide that digests colanic acid under conditions that digest the colonic acid, and separating the plasmid DNA from the digested colonic acid.
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