Methods of Preparation and Manufacture of Biocompatible Solid-Phase Microextraction Coatings and Coated Devices
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May 23, 2012
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Mar 11, 2002
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Abstract
A process for manufacturing a fiber or other device with a biocompatible coating for using the fiber in solid phase microextraction (SPME) of a small molecule of interest from a matrix. The process includes the step of coating the fiber/device with a coating of a biocompatible polymer and a solvent having solid phase microextraction (SPME) particles with pores dimensioned to absorb the small molecule of interest from the matrix suspended therein. The process also includes the steps of drying the coated fiber/device to remove the solvent and curing the dried coated fiber at an elevated temperature.
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