VIRAL POLYPEPTIDES AND METHODS
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United States of America Patent
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Issued Date -
Sep 6, 2012
app pub date -
Sep 16, 2009
filing date -
Sep 16, 2008
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Abandoned
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Abstract
The invention is directed to polypeptides and polypeptide fragments from HIV-1 envelope (Env) proteins following the characterization of Env structures from environments where HIV isolates expose conserved neutralization-sensitive Env structures. There is provided a polypeptide being all or a fragment of an HIV-1 envelope protein from a transmission strain of HIV-1, the polypeptide having neutralization sensitive epitopes that are accessible.
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