Novel Processes

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United States of America Patent

APP PUB NO 20120220779A1
SERIAL NO

13503867

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides processes useful for preparing 5-lipoxygenase activating protein (FLAP) inhibitors and their intermediates. In particular, processes for preparing 3-[3-(tert-butylsulfanyl)-1-[4-(6-ethoxy-pyridin-3-yl)benzyl]-5-(5-methyl-pyridin-2-yl-methoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid, the anhydrous Form C polymorph of sodium 3-[3-(tert-butylsulfanyl)-1-[4-(6-ethoxy-pyridin-3-yl)benzyl]-5-(5-methyl-pyridin-2-yl-methoxy)-1H-indol-2-yl]-2,2-dimethyl-propionate, and intermediates useful in said processes are provided.

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Patent Owner(s)

Patent OwnerAddress
PANMIRA PHARMACEUTICALS LLC9535 WAPLES STREET SUITE 100 SAN DIEGO CA 92121

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Crawford, Claire Frances Stevenage, GB 4 3
Garcia, Sandrine Stevenage, GB 1 2
Graham, Jonathan Paul Stevenage, GB 2 2
Harling, Sandra Jane Stevenage, GB 1 2
Henley, Nicholas Paul Stevenage, GB 2 4
Hermitage, Stephen Andrew Stevenage, GB 2 34
Hutchinson, John Howard San Giego, US 91 911
Keel, Trevor Raymond Stevenage, GB 5 8
Kennedy, Andrew Stevenage, GB 59 431
Mason, Andrew McMurtrie Stevenage, GB 41 158
Scott, Mark Simon Stevenage, GB 1 2
Smith, Neil Michael Stevenage, GB 4 7
Stock, Nicholas Simon San Diego, US 47 540
Tateno, Yuichi Stevenage, GB 1 2
Trouw, Leontine Saskia Stevenage, GB 3 33
Turner, Peter Graham Stevenage, GB 1 2
Wallis, Christopher John Stevenage, GB 5 8
Willacy, Robert David Stevenage, GB 7 27

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