GPCR Expressing Cell Lines and Antibodies
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United States of America Patent
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Issued Date -
Aug 30, 2012
app pub date -
May 14, 2012
filing date -
Oct 28, 2005
priority date (Note) -
Abandoned
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Abstract
The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.
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