Singlet Oxygen Production and Dosimetry for Photodynamic Therapy
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United States of America Patent
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Issued Date -
Aug 16, 2012
app pub date -
Feb 10, 2012
filing date -
Feb 10, 2011
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
An apparatus for photodynamic therapy (PDT) includes a light source configured to provide excitation light for a photosensitizer, an optical system configured to direct the excitation light to a target region and receive light emitted by the photosensitizer and/or singlet oxygen generated in the target region, and a detection system configured to receive the light emitted by the photosensitizer and/or the singlet oxygen. The apparatus also includes a filter system configured to spectrally discriminate between emission from the photosensitizer and the singlet oxygen and a processor configured to determine concentrations of the singlet oxygen and/or the photosensitizer based on an emission signal measured by the detection system.
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