INTRACELLULAR TOLL-LIKE RECEPTORS PATHWAYS AND AXONAL DEGENERATION
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Issued Date -
Aug 16, 2012
app pub date -
Jan 30, 2012
filing date -
Jul 23, 2009
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Abstract
The present invention is directed to the identification of novel mechanisms involved in the initiation and spreading of axonal degeneration. In particular, the instant invention relates to the identification of a relationship between Toll-Like Receptors (TLRs) and axonal degeneration and the use of TLR inhibitors as antagonists of axonal degeneration.
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