METHODS OF USING CD44 FUSION PROTEINS TO TREAT CANCER
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United States of America Patent
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Issued Date -
Aug 16, 2012
app pub date -
Aug 16, 2010
filing date -
Aug 21, 2009
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Abandoned
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Abstract
Pharmaceutical compositions and methods for treating cancer using CD44 antagonists are disclosed. In certain aspects, these pharmaceutical compositions and methods include treating a mammal having a cancer, such as glioma, colon cancer, breast cancer, prostate cancer, ovarian cancer, lung cancer, renal cell carcinoma, gastric cancer, esophageal cancer, head cancer, neck cancer, pancreatic cancer, or melanoma, with a CD44 fusion protein. These CD44 fusion proteins include CD44-Fc fusions and can be used to detect hyaluronan.
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