METHODS OF TREATING DISEASES WITH PROANTHOCYANIDIN OLIGOMERS SUCH AS CROFELEMER

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United States of America Patent

APP PUB NO 20120202876A1
SERIAL NO

13500589

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are methods of treating diseases including gastrointestinal disorders, such as secretory diarrheas, with the proanthocyanidin oligomer, crofelemer. Also disclosed is the anti-secretory effect of crofelemer on Calcium-activated chloride channels (CaCC) and Cystic fibrosis transmembrane conductance regulator (CFTR).

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Patent Owner(s)

Patent OwnerAddress
NAPO PHARMACEUTICALS INC201 MISSION STREET SUITE 2375 SAN FRANCISCO CA 94105

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chaturvedi, Pravin San Francisco, US 10 244
Namkung, Wan San Francisco, US 6 10
Tradtrantip, Lukmanee San Francisco, US 6 13
Verkman, Alan S San Francisco, US 48 115

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