COMPOSITIONS COMPRISING CYCLIC AMP ENHANCERS AND/OR EP LIGANDS, AND METHODS OF PREPARING AND USING THE SAME

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United States of America Patent

SERIAL NO

13257290

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Abstract

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Provided are improved pharmaceutical compositions that comprise ligands or agonists to prostaglandin EP receptors, and/or cyclic AMP enhancers, and suitable organic solvents that are substantially free of methyl acetate, the compositions being provided for storage and/or use in an endotoxin-free vessel, such as a tube or PE bag. The compositions are suitable for in vitro, ex vivo, and in vivo use, and in particular for ex vivo therapeutic use, such as in hematopoietic stem cell transplants. Also provided are methods of using the compositions in ex vivo therapeutic applications, and methods of preparing the compositions. Kits with instructions on use are also provided.

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Patent Owner(s)

Patent OwnerAddress
FATE THERAPEUTICS INC12278 SCRIPPS SUMMIT DRIVE SAN DIEGO CA 92131

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Farouz, Francine S La Jolla, US 12 157
Mendlein, John D Leucadia, US 118 2854
Shoemaker, Daniel San Diego, US 34 1437
Thies, R Scott San Diego, US 30 587

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