Therapeutic Monoclonal Antibodies that Neutralize Botulinum Neurotoxins
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United States of America Patent
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Issued Date -
Jul 12, 2012
app pub date -
Jul 1, 2011
filing date -
Jan 27, 2005
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Abandoned
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Abstract
This invention provides antibodies that specifically bind to and neutralize botulinum neurotoxin type A (BoNT/A) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.
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