Delivery of Polynucleotides Across the Blood-Brain-Barrier Using Recombinant AAV9

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United States of America Patent

APP PUB NO 20120177605A1
SERIAL NO

13270840

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to methods and materials useful for systemically delivering polynucleotides to the spinal cord. Use of the methods and materials is indicated, for example, for treatment of lower motor neuron diseases such as spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) as well as Pompe disease and lysosomal storage disorders.

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Patent Owner(s)

Patent OwnerAddress
NATIONWIDE CHILDREN'S HOSPITAL700 CHILDRENS DRIVE COLUMBUS OH 43205

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Foust, Kevin Westerville, US 19 183
Kaspar, Brian K Westerville, US 45 382

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