CANCER SPECIFIC TRANSCRIPT VARIANTS
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United States of America Patent
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Issued Date -
Jul 5, 2012
app pub date -
Dec 17, 2009
filing date -
Dec 17, 2008
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Abstract
The present inventors here present a novel strategy for identification of RNA transcript variants and demonstrate that these can be correlated to disease states in mammals such as cancer. In particular, the transcript variants show prevalence and specificity to cancer, and thus also show clinical applicability in e.g. cancer diagnostics and prognostics, treatment and therapeutics. The present inventors have identified RNA transcript variants of VNN1 that can be used as biomarkers. The RNA transcript variant may also be used as biomarkers for diagnosing, prognosing, and/or monitoring a cancer.
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