METHOD AND COMPOSITIONS FOR ASSISTING IN DIAGNOSING AND/OR MONITORING BREAST CANCER PROGRESSION

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United States of America Patent

APP PUB NO 20120172238A1
SERIAL NO

13497062

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Abstract

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The present invention relates to a method for assisting in diagnosing breast cancer and/or monitoring breast cancer progression in a given sample based on the analysis of differential DNA methylation patterns. More particularly, the method is directed to the identification of one or more epigenetic markers that derive from the application of a variety of statistical methods in order to point out the prognostic significance of the difference in methylation states at one or more genomic loci and predict whether the sample analyzed has a good or bad prognosis following treatment.

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Patent Owner(s)

Patent OwnerAddress
KONINKLIJKE PHILIPS ELECTRONICS N V5621 BA EINDHOVEN
COLD SPRING HARBOR1 BUNGTOWN ROAD NEW YORK NY 11724

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hicks, James Bruce Lattingtown, US 5 8
Kamalakaran, Sitharthan Pelham, US 30 144
Varadan, Vinay New York, US 28 120

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