CELL ATTACHMENT COATINGS AND METHODS
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United States of America Patent
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Issued Date -
Jul 5, 2012
app pub date -
Dec 30, 2011
filing date -
Dec 30, 2010
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Abstract
Cell attachment coatings for articles such as implantable medical devices and cell culture vessels are disclosed. The coatings include an intermediate coater layer which includes a sulfonated component that is bonded in the coating by reacted aryl ketone functional groups. The coating also include a second coated layer including an immobilized ECM protein or peptide that includes an active portion of an ECM protein that is able to serve as an outer layer to contact cells during use. The coatings promoted enhanced cell binding and growth.
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