In-Line Derivatization Of Polyaminosaccharide Polymer For Analytical Determination
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United States of America Patent
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Issued Date -
Jun 28, 2012
app pub date -
Dec 28, 2011
filing date -
Dec 28, 2010
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Abstract
An analytic method for the determination of the concentration of polysaccharide polymer in solution comprises the in-line derivatization of the polymer by reaction with sulfonate dye. The reaction results in an analyte-derivative, carried in a mobile phase, that can be detected and quantitatively determined by ultraviolet absorption or by fluorescence measurement. The method can provide sensitive and precise measurement in spite of limited solubility of the analyte.
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