GENOMIC EDITING OF GENES INVOLVED IN MACULAR DEGENERATION
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United States of America Patent
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Issued Date -
Jun 21, 2012
app pub date -
Jul 23, 2010
filing date -
Dec 4, 2008
priority date (Note) -
Abandoned
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Abstract
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with MD. In particular, the animals or cells are generated using a zinc finger nuclease-mediated editing process. Also provided are methods of using the genetically modified animals or cells disclosed herein to study MD development and methods of assessing the effects of agents in genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with MD.
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