COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS
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United States of America Patent
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Issued Date -
Jun 14, 2012
app pub date -
May 31, 2011
filing date -
May 28, 2010
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Abstract
High throughput and virtual screening methods are disclosed that can identify potential anti-viral agents. The virtual screening methods identify agents that interact with a viral nucleoprotein binding site. The high throughput methods identify compounds that inhibit viral infection by binding to viral nucleoprotein. Also disclosed are pharmaceutical formulations useful for treating or preventing viral infections, especially influenza A.
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