PROCESS FOR PRODUCTION OF BIOARTIFICIAL ORGAN
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United States of America Patent
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Issued Date -
Jun 14, 2012
app pub date -
Aug 11, 2010
filing date -
Aug 17, 2009
priority date (Note) -
Abandoned
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Abstract
A method for inducing the differentiation of stem cells into tissue cells; a bioartificial organ, which contains the tissue cells; and a material for medical purposes, which contains the bioartificial organ are disclosed. Stem cells capable of proliferation, self-replication and differentiation are used and cultured by a hanging-drop method to three-dimensionally construct a cell mass of embryoid bodies, and the cell mass is cultured in the presence of HGF, GDNF, b-FGF, BMP7 and EGF. In this manner, the stem cells can be differentiated into tissue cells. A bioartificial organ can be produced using cells that have been differentiated into the tissue cells. Further, a material for medical purposes can be provided.
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