Diagnostic Markers for Ankylosing Spondylitis

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United States of America Patent

APP PUB NO 20120148574A1
SERIAL NO

13122366

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention discloses methods and agents for diagnosing the presence or risk of development of ankylosing spondylitis (AS) in mammals, which are based on the detection of polymorphisms within any one or more of the ARTS-1 gene, the IL-23R gene, the TNFR1 gene locus, the TRADD gene locus, the IL-1R1 gene locus, the IL-1R2 gene locus, the CD74 gene locus and the chromosome loci 2P15, 2Q31.3 and 4Q13.1. The present invention also features methods for the treatment or prevention of AS based on the diagnostic methods.

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Patent Owner(s)

Patent OwnerAddress
BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM201 WEST 7TH STREET SUITE 820 AUSTIN TX 78701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Matthew Arthur Fig Tree Pocket, AU 2 3
Reveille, John Duffin Houston, US 1 2
Wordsworth, Bryan Paul Oxford, GB 1 2

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