METHOD FOR PRODUCING T CELL POPULATION UNDER PRESENCE OF RETINOIC ACID
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United States of America Patent
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Issued Date -
Jun 7, 2012
app pub date -
Aug 24, 2010
filing date -
Aug 25, 2009
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Abandoned
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Abstract
Disclosed is a method for producing a cell population containing memory-like T cells, said method being characterized by including a step for in vitro culturing of a cell population containing T cells or T cell precursor cells using a retinoic acid and a CD3 ligand. Further disclosed is a method for producing a cell population wherein the proportion of memory-like T cells is increased and wherein a desired gene is introduced with a high efficiency and is highly expressed.
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