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Abstract

An electro-spray delivery device for delivering a stream of charged micro-droplets of a conductive fluid, and which a capillary tube having a proximal end in fluid communication with a source of conductive fluid and a distal end opposite the proximal end. The device also includes a solid guide wire coaxially disposed at least partially within the capillary tube to form an annular passage therein, and which has a distal tip projecting beyond the distal end of the capillary tube. At least one of the capillary tube and guide wire is conductive and in electrical communication with a high-voltage source to electrically charge the conductive fluid flowing through the annular passage and wetting the distal tip of the guide wire. The electrospray delivery device further includes a grounding electrode that is located a predetermined distance from the distal tip of the guide wire and which is in electrical communication with a source of ground. A voltage differential between the charged fluid and the grounding electrode draws the charged fluid away from the distal end of the capillary tube to form a cone jet about the end face of the distal tip discharging a stream of charged micro-droplets.

First Claim