Microfluidic Device and Related Methods
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United States of America Patent
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Issued Date -
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app pub date -
Feb 12, 2010
filing date -
Mar 4, 2009
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A combinatorial microenvironment generator is configured for the generation of arbitrary, user-defined, steady-state, concentration gradients with negligible to no flow through the growth medium to perturb diffusion gradients or cellular growth. More importantly, the absolute concentrations and/or gradients can be dynamically altered upon request both spatially and temporally to impose tailored concentration fields for in-situ stimulus studies. Here, diffusion occurs via an array of ports, each of which can be an independently controlled source/sink. Together, the array of ports establishes a user-defined, 3D concentration profile. Useful methods related to this device are also provided.
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Patent Citation Ranking
- 25 Citation Count
- C12Q Class
- 82.47 % this patent is cited more than
- 13 Age