Efficient Method for Preparing Functionalized Benzosuberenes
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United States of America Patent
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Issued Date -
May 24, 2012
app pub date -
Nov 16, 2011
filing date -
Nov 16, 2010
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Abandoned
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Abstract
The disclosed process can efficiently synthesize functionalized benzosuberenes. The process provides an improved method of production of benzosuberene and compounds containing a benzosuberene moiety, which is characterized by a ring closing methodology comprising reaction of a 5-phenylpentanoic acid with Eaton's reagent to form the benzosuberone. The process, optionally, further includes steps for adding a functional group at the ketone position.
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