TGF-BETA PATHWAY INHIBITORS FOR ENHANCEMENT OF CELLULAR REPROGRAMMING OF HUMAN CELLS

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United States of America Patent

APP PUB NO 20120122212A1
SERIAL NO

13203780

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Abstract

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The present disclosure provides methods and compositions to enhance reprogramming in human cells. In some cases, the method includes contacting human cells with an inhibitor of the TGFβ pathway, for example a TGFβ receptor (TGFβR) inhibitor in combination with one or more induction factors.

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Patent Owner(s)

Patent OwnerAddress
IPIERIAN INC951 GATEWAY BOULEVARD SOUTH SAN FRANCISCO CA 94080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bakhtiarova, Adel Woodside, US 1 29
Dimos, John So. San Francisco, US 2 35
Grskovic, Marica So. San Francisco, US 10 114
Strulovici, Berta So. San Francisco, US 6 109
Wang, Weidong So. San Francisco, US 86 497

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