Means And Methods For Counteracting, Preventing And/Or Determining Heart Failure, Or A Risk Of Heart Failure
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United States of America Patent
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Issued Date -
May 10, 2012
app pub date -
Apr 29, 2010
filing date -
Apr 29, 2009
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Abstract
The present invention relates to a method for diagnosing and/or prognosing heart failure in a subject the method comprising the step of determining the level of at least one genetic marker in a body fluid sample obtained from said subject, wherein said at least one genetic marker is an mi RNA. The invention further relates to a method for treating or preventing heart failure in a subject the method comprising the step of decreasing within said subject the expression, amount, and/or activity of at least one mi RNA, or decreasing within said subject the interaction of at least one mi RNA with its m RNA target or increasing within said subject the expression, amount, and/or activity of the m RNA target of at least one mi RNA.
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