METHODS AND KITS FOR HIGH EFFICIENCY ENGINEERING OF CONDITIONAL MOUSE ALLELES
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United States of America Patent
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Issued Date -
May 3, 2012
app pub date -
Jun 28, 2010
filing date -
Jun 29, 2009
priority date (Note) -
Abandoned
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Abstract
The present invention concerns methods and kits for the direct, targeted engineering of conditional alleles in rodent embryonic stem cells in which the conditional allele is replaced with a DNA of interest without first introducing heterotypic recombination sites, thus providing high efficiency targeted exchange of genetic material.
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