METHODS OF PROGNOSIS IN CHRONIC KIDNEY DISEASE
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United States of America Patent
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Issued Date -
May 3, 2012
app pub date -
Oct 29, 2009
filing date -
Oct 31, 2008
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Abandoned
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Abstract
The present invention relates to methods of prognosing the survival of a diseased subject, particularly a subject with chronic kidney disease (CKD), as well as selecting an end-stage renal disease subject for a kidney transplant. The methods involve detecting an elevated amount of macrophage inhibitory cytokine-1 (MIC-1) in a test body sample from the diseased subject. A method of preventing or reducing the risk of death in a CKD subject which involves removing or inactivating MIC-1 present in the blood, plasma or serum of the subject, is also disclosed.
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