CATHEPSIN CYSTEINE PROTEASE INHIBITORS FOR THE TREATMENT OF VARIOUS DISEASES

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20120101053A1
SERIAL NO

13379200

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to compounds capable of inhibiting and/or decreasing the activity of one or more cathepsins, thereby treating and/or preventing various disease states associated with one or more cysteine proteases including, but not limited to, cathepsins and papain-like cysteine proteases. Disease states treated and/or prevented by the compounds of the invention include, but are not limited to, mammalian parasitic diseases in which the parasite utilizes a critical cysteine protease from the papain family. Examples of parasitic diseases to be treated or prevented by the compounds of the invention include, but are not limited to, toxoplasmosis, malaria, African trypanosomiasis, Chagas disease, leishmaniasis, coccidiosis, giardiosis, cryptosporidiosis or schistosomiasis.

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Patent Owner(s)

Patent OwnerAddress
MERCK CANADA INCKIRKLAND QC H9H 3L1

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beaulieu, Christian Laval, CA 15 127
Black, Cameron Baie d' Urfe, CA 51 1453

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