IDENTIFICATION AND DIFFERENTIATION OF NUCLEIC ACID SEQUENCE USING TEMPERATURE-DEPENDENT HYBRIDIZATION
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United States of America Patent
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Issued Date -
Apr 26, 2012
app pub date -
Dec 7, 2009
filing date -
Dec 10, 2008
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Abandoned
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Abstract
Oligonucleotide probes are provided that are capable of hybridizing to different target nucleic acid sequences in a temperature-dependent manner allowing for detection of more than one target sequence by the same probe or by different probes having reporter labels with identical or similar detection characteristics. Also provided is a method for detecting target nucleic acid sequences using an oligonucleotide probe capable of hybridizing to the sequences in a temperature-dependent manner or using different probes having reporter labels with identical or similar detection characteristics.
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