Sustained-Release Tablet and Process for Preparing the Same
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United States of America Patent
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Issued Date -
Apr 26, 2012
app pub date -
Oct 21, 2011
filing date -
Oct 21, 2010
priority date (Note) -
Abandoned
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Abstract
A method for producing a sustained-release tablet having improved stability and content uniformity is provided. The method involves first preparing a core tablet by granulating, drying, milling, blending, and compressing a mixture of active and inactive ingredients. Four coating layers are applied to the core tablet: an inner layer, an enteric coating layer, an active layer, and an outer layer. The active ingredient may be a tetracycline, such as doxycycline. A sustained-release tablet prepared according to the method is also described.
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