MATERIAL AND PROCESS FOR INCORPORATION OF LOW DOSAGE ACTIVE PHARMACEUTICAL INGREDIENTS AND USE THEREOF

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United States of America Patent

APP PUB NO 20120100211A1
SERIAL NO

13261010

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A low dose API pharmaceutical tablet having excellent content uniformity is provided. The tablet is formed by spray coating a support excipient with the API. The resulting composition is suitable for direct compression tablet formulation without the need for an additional granulation step to uniformly coat the API onto the support excipient. The support excipient comprises microcrystalline cellulose, a binder and a disintegrant, and is formed by spraying a homogeneous slurry of the support excipient components.

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Patent Owner(s)

Patent OwnerAddress
AVANTOR PERFORMANCE MATERIALS INC3477 CORPORATE PARKWAY SUITE 200 CENTER VALLEY PA 18034

International Classification(s)

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  • 2010 Application Filing Year
  • A61K Class
  • 10962 Applications Filed
  • 7633 Patents Issued To-Date
  • 69.64 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2010201120122013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deorkar, Nandu Cedar Knolls, US 29 116
Farina, James Nazareth, US 11 15
Miinea, Liliana Easton, US 7 9

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges842417611114322011046329171032401 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500

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